SCHEMBL9301795

SCHEMBL9301795

C=CCc1cc(-c2cc(CC=C)nc(CC=C)c2)cc(CC=C)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
PDE4A P27815 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
XDH P47989 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALDH2 P05091 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
AKR1B1 P15121 1/20 0.31
HPGD P15428 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
PPARG P37231 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARD Q03181 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2410720 0.87 L3MBTL1 (0.40) PDE4APDE4CPDE4DMEN1ALDH1A1
SCHEMBL9403340 0.84 PDE4A (0.36) GABRA1GABRB2PDE4APDE4CPDE4D
SCHEMBL797991 0.82 XDH (0.40) GABRA1GABRB2PDE4APDE4CPDE4D
SCHEMBL9346680 0.80 IMPDH2 (0.33) XDHNPSR1
SCHEMBL2413761 0.77 ALDH1A1 (0.43) GABRA1MEN1ALDH1A1MAPTHPGD
SCHEMBL10582024 0.75 IMPDH2 (0.33) XDHNPSR1
SCHEMBL11458793 0.75 DCTPP1 (0.31) GABRA1GABRB2
SCHEMBL249852 0.74 GABRA1 (0.40) GABRA1GABRB2PDE4APDE4CPDE4D
SCHEMBL11221267 0.72 PDE4A (0.31) PDE4APDE4CPDE4D
SCHEMBL9301260 0.72 GABRA1 (0.39) GABRA1GABRB2PDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5336448-A Light filters; reflectance mirrors GENTEX CORPORATION (US) 1994-08-09 US disclosed
US-5278693-A Tinted solution-phase electrochromic devices GENTEX CORPORATION (US) 1994-01-11 US disclosed
EP-0552012-A2 Tinted solution-phase electrochromic devices GENTEX CORPORATION (US) 1993-07-21 EP disclosed