Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 known ✓ | P41231 | 2/20 | 0.40 |
| ▸ | DHFR known ✓ | P00374 | 1/20 | 0.39 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 9/20 | 0.50 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012347 | 1.00 | RAD51 (0.50) | RAD51P2RY2ENTPD1MAPTALDH1A1 | |
| SCHEMBL8011898 | 0.97 | RAD51 (0.50) | RAD51P2RY2ENTPD1MAPTALDH1A1 | |
| SCHEMBL8011911 | 0.97 | RAD51 (0.50) | RAD51P2RY2ENTPD1MAPTALDH1A1 | |
| SCHEMBL8011882 | 0.91 | RAD51 (0.55) | RAD51P2RY2MAPTALDH1A1RAB9A | |
| SCHEMBL8011892 | 0.91 | RAD51 (0.55) | RAD51P2RY2MAPTALDH1A1RAB9A | |
| SCHEMBL8011912 | 0.91 | RAD51 (0.55) | RAD51P2RY2MAPTALDH1A1RAB9A | |
| SCHEMBL8011925 | 0.91 | RAD51 (0.55) | RAD51P2RY2MAPTALDH1A1RAB9A | |
| SCHEMBL8432740 | 0.87 | ENPP2 (0.43) | MAPTALDH1A1RAB9ADHFRMEN1 | |
| SCHEMBL8432719 | 0.87 | ENPP2 (0.43) | MAPTALDH1A1RAB9ADHFRMEN1 | |
| SCHEMBL9551808 | 0.86 | ENPP2 (0.43) | MAPTALDH1A1RAB9ADHFRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647878-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0532042-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5618660-A | IRRIDIUM METAL DOPANT SILVERCHLROBROMIDE GRAINS; SILVERHALIDE EMULSION LAYER IS SPECTRALLY SENSITIZED WITH A CYANINE DYE AND CHEMICALLY SENSITIZED WITH GOLD AND SELENIUM COMPOUNDS; HIGH SENSITIVITY AND HIGH CONTRAST IMAGE | FUJI PHOTO FILM CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| EP-0474047-B1 | Silver halide emulsion | FUJI PHOTO FILM CO LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| EP-0383265-B1 | Method for forming color image | FUJI PHOTO FILM CO LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5508161-A | SPECTRALLY SENSITIZED WITH A COMBINATION OF AT LEAST TWO J-BAND TYPE SENSITIZING DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5489505-A | ON A SUPPORT ATLEAST ONE SILVER HALIDE EMULSION AND ATLEAST ONE METHINE DYE; STORAGE STABILITY AND HIGH SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0563860-B1 | Photographic silver halide photosensitive material | FUJI PHOTO FILM CO LTD (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0647878-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-12 | — | — | EP | disclosed |
| EP-0369410-B1 | Silver halide photographic emulsion | FUJI PHOTO FILM CO LTD (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0563860-A2 | Photographic silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5223389-A | Containing at least one cyanine or merocyanine dye; storage stability; high speed processing | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0532042-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5162195-A | Scanning exposure to three wavelengths, indole cyanine dye sensitizer | FUJI PHOTO FILM CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5149619-A | Infrared sensitized | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0474047-A1 | Silver halide emulsion | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |