Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019079 | 0.86 | KDM4E (0.51) | HTR6RXFP1MAPTGAATP53 | |
| SCHEMBL8021669 | 0.86 | HPGD (0.45) | HTR6RXFP1MAPTGAATP53 | |
| SCHEMBL8028243 | 0.81 | HTR6 (0.59) | HTR6RXFP1MAPTGAATP53 | |
| SCHEMBL8030043 | 0.80 | HTR6 (0.50) | HTR6RXFP1MAPTGAATP53 | |
| SCHEMBL8026556 | 0.77 | KDM4E (0.64) | HTR6RXFP1MAPTGAATP53 | |
| SCHEMBL8019460 | 0.77 | HTR6 (0.60) | HTR6RXFP1MAPTGAATP53 | |
| SCHEMBL8019523 | 0.76 | HTR6 (0.70) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL8019526 | 0.73 | THRB (0.65) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL8029242 | 0.73 | CRHBP (0.74) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL8019551 | 0.72 | HTR6 (0.75) | HTR6RXFP1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093934-A2 | SUBSTITUTED 3-SULPHONYL-[1,2,3]TRIAZOLO [1,5-A]PYRIMIDINES-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, MEDICINAL SUBSTANCE, PHARMACEUTICAL COMPOSITION, MEDICINAL PREPARATION AND METHODS FOR THE PRODUCTION THEREOF | ALLA CHEM, LLC (US) | 2009-07-30 | — | — | WO | disclosed |