Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042788 | 0.83 | HSD17B10 (0.42) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8042980 | 0.83 | ALDH1A1 (0.41) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8044808 | 0.83 | RXRA (0.40) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8050732 | 0.83 | RXRA (0.43) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8033764 | 0.81 | HTT (0.46) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8041806 | 0.80 | KMT2A (0.38) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8044465 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2MEN1LMNA | |
| SCHEMBL8043875 | 0.79 | UBE2M (0.37) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8716288 | 0.79 | CYP2C19 (0.47) | RXRARXRBRXRGALDH1A1HCAR2 | |
| SCHEMBL8042066 | 0.78 | RXRA (0.39) | RXRARXRBRXRGALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |