Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042788 | 0.93 | HSD17B10 (0.42) | HTTPOLBHPGDCYP2C19ALDH1A1 | |
| SCHEMBL8042980 | 0.88 | ALDH1A1 (0.41) | HTTPOLBCYP2C19ALDH1A1KMT2A | |
| SCHEMBL8043875 | 0.88 | UBE2M (0.37) | HTTPOLBHPGDALDH1A1MAPT | |
| SCHEMBL8716288 | 0.88 | CYP2C19 (0.47) | HTTPOLBHPGDCYP2C19ALDH1A1 | |
| SCHEMBL8032986 | 0.85 | RXRA (0.34) | HTTPOLBHPGDCYP2C19ALDH1A1 | |
| SCHEMBL8041806 | 0.83 | KMT2A (0.38) | POLBHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL8050397 | 0.82 | ALDH1A1 (0.40) | HTTPOLBHPGDALDH1A1KMT2A | |
| SCHEMBL8033751 | 0.81 | RXRA (0.43) | HTTPOLBHPGDALDH1A1KMT2A | |
| SCHEMBL8046035 | 0.81 | HTT (0.41) | HTTPOLBHPGDCYP2C19ALDH1A1 | |
| SCHEMBL8033250 | 0.80 | HTT (0.41) | HTTPOLBHPGDCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |