Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 3/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405116 | 0.84 | PTPN1 (0.40) | PARP10PTGESALOX5FFAR1PTPN1 | |
| SCHEMBL8038304 | 0.84 | PTPN1 (0.40) | PARP10PTGESALOX5FFAR1PTPN1 | |
| SCHEMBL8039546 | 0.84 | PTPN1 (0.40) | PARP10PTGESALOX5FFAR1PTPN1 | |
| SCHEMBL8039708 | 0.84 | PTPN1 (0.40) | PARP10PTGESALOX5FFAR1PTPN1 | |
| SCHEMBL8039689 | 0.83 | PTPN1 (0.38) | PARP10PTGESALOX5FFAR1PTPN1 | |
| SCHEMBL8038284 | 0.82 | ALDH1A1 (0.49) | PARP10PTPN1 | |
| SCHEMBL8041238 | 0.80 | LTA4H (0.51) | PTPN1 | |
| SCHEMBL6408806 | 0.80 | ALOX5 (0.50) | ALOX5FFAR1PTPN1 | |
| SCHEMBL8041220 | 0.79 | MTNR1A (0.41) | GPR88PTPN1 | |
| SCHEMBL8041172 | 0.79 | TSPO (0.40) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |