Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555090 | 0.77 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL988672 | 0.73 | POLB (0.37) | TRPA1ATM | |
| SCHEMBL6676515 | 0.72 | SCN2A (0.43) | GABRA1GABRB2SCN2AATM | |
| SCHEMBL7524517 | 0.70 | ALDH1A1 (0.37) | GABRA1GABRB2SCN2ATRPA1ATM | |
| SCHEMBL7523209 | 0.69 | GABRA1 (0.41) | GABRA1GABRB2SCN2ATRPA1ATM | |
| SCHEMBL7525374 | 0.67 | ALDH1A1 (0.36) | GABRA1GABRB2TRPA1ATM | |
| SCHEMBL8390355 | 0.67 | GABRA1 (0.42) | GABRA1GABRB2SCN2ATRPA1ATM | |
| SCHEMBL9217674 | 0.66 | TRPA1 (0.41) | TRPA1ATM | |
| SCHEMBL7519263 | 0.66 | SCN2A (0.43) | GABRA1GABRB2SCN2ATRPA1ATM | |
| SCHEMBL7521592 | 0.65 | ALOX15 (0.39) | GABRA1GABRB2SCN2ATRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133467-A | ANTIATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0996623-A1 | 2,6-DI-t-BUTYL-4- (DIMETHYL-4-METHOXYPHENYLSILYL) -METHYLOXY]PHENOL AND 2,6-DI-t-BUTYL-4- (DIMETHYL-2-METHOXY-PHENYLSILYL) -METHYLOXY]PHENOL | HOECHST MARION ROUSSEL, INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1998058937-A1 | 2,6-DI-t-BUTYL-4-[ (DIMETHYL-4-METHOXYPHENYLSILYL) -METHYLOXY]PHENOL AND 2,6-DI-t-BUTYL-4-[ (DIMETHYL-2-METHOXY-PHENYLSILYL) -METHYLOXY]PHENOL | HOECHST MARION ROUSSEL, INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| EP-0732928-A1 | METHOD OF LOWERING SERUM CHOLESTEROL LEVELS WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015760-A1 | METHOD OF LOWERING SERUM CHOLESTEROL LEVELS WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | MERRELL PHARMACEUTICALS INC. (US) | 1995-06-15 | — | — | WO | disclosed |