Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044443 | 0.90 | ALDH1A1 (0.49) | CYP19A1NPC1MEN1KMT2ALMNA | |
| SCHEMBL8041897 | 0.88 | ALDH1A1 (0.47) | MEN1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL8043675 | 0.82 | KIT (0.39) | CYP19A1CYP3A4CYP2C19HSD17B10KDM4E | |
| SCHEMBL8033588 | 0.81 | HSD17B10 (0.45) | NPC1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL8043953 | 0.80 | TDP1 (0.47) | KMT2ALMNACYP3A4MAPTMAPK1 | |
| SCHEMBL8048723 | 0.80 | VCP (0.48) | NPC1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL8044092 | 0.80 | KMT2A (0.45) | NPC1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL8047667 | 0.79 | LMNA (0.40) | CYP19A1NPC1MEN1KMT2ALMNA | |
| SCHEMBL8044812 | 0.79 | ALDH1A1 (0.52) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL8048028 | 0.79 | KMT2A (0.44) | NPC1MEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |