Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033963 | 0.89 | RAB9A (0.44) | RAB9AALDH1A1NPC1HPGDLMNA | |
| SCHEMBL8043417 | 0.83 | HDAC6 (0.36) | RAB9ANPC1HPGDLMNAKDM4E | |
| SCHEMBL8042849 | 0.81 | ALDH1A1 (0.33) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL8032788 | 0.81 | PTGS2 (0.33) | KDM4EL3MBTL1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8042797 | 0.81 | MAPK8 (0.43) | RAB9AALDH1A1NPC1MAPTHTT | |
| SCHEMBL8046313 | 0.79 | ALDH1A1 (0.35) | RAB9AALDH1A1NPC1HPGDLMNA | |
| SCHEMBL8042548 | 0.78 | TRPM8 (0.34) | RAB9AALDH1A1NPC1LMNAL3MBTL1 | |
| SCHEMBL8042933 | 0.78 | DCUN1D1 (0.37) | RAB9AALDH1A1NPC1LMNAKDM4E | |
| SCHEMBL8047827 | 0.78 | NPC1 (0.41) | RAB9AALDH1A1NPC1HDAC3HDAC4 | |
| SCHEMBL8037025 | 0.77 | MEN1 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |