Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042849 | 0.92 | ALDH1A1 (0.33) | ALDH1A1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL8042548 | 0.87 | TRPM8 (0.34) | ALDH1A1RAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL8044846 | 0.81 | RAB9A (0.42) | ALDH1A1RAB9AMAPTKMT2AMAPK1 | |
| SCHEMBL8044527 | 0.81 | RAB9A (0.35) | ALDH1A1RAB9AMAPTKMT2AMAPK1 | |
| SCHEMBL8032365 | 0.80 | MAPK8 (0.49) | ALDH1A1RAB9AMAPTKMT2AMAPK1 | |
| SCHEMBL8042291 | 0.79 | USP7 (0.30) | — | |
| SCHEMBL8044714 | 0.79 | RAB9A (0.34) | ALDH1A1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8037025 | 0.77 | MEN1 (0.37) | KMT2AMEN1 | |
| SCHEMBL8042296 | 0.74 | RAB9A (0.39) | ALDH1A1RAB9AMAPTKMT2AMAPK1 | |
| SCHEMBL8041832 | 0.73 | RAB9A (0.53) | ALDH1A1RAB9AKMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |