Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044888 | 0.90 | MEN1 (0.53) | HPGDEP300MEN1KMT2APOLB | |
| SCHEMBL8044812 | 0.88 | ALDH1A1 (0.52) | HPGDMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8046294 | 0.85 | UBE2M (0.45) | HPGDKMT2APOLBALDH1A1MAPK1 | |
| SCHEMBL8043968 | 0.85 | MEN1 (0.45) | HPGDEP300MEN1KMT2APOLB | |
| SCHEMBL8042159 | 0.83 | RAB9A (0.47) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8042528 | 0.83 | ALDH1A1 (0.45) | HPGDKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8032329 | 0.83 | RECQL (0.53) | HPGDEP300MEN1KMT2APOLB | |
| SCHEMBL8043233 | 0.83 | PTGS2 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8034319 | 0.82 | ALDH1A1 (0.51) | HPGDMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8044654 | 0.82 | MAPT (0.44) | HPGDMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |