Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | EIF4E | P06730 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714734 | 0.91 | KMT2A (0.43) | MEN1KMT2ARAB9ANPC1EIF4E | |
| SCHEMBL8050863 | 0.83 | ALOX5 (0.35) | MEN1KMT2AALOX5EIF4ELMNA | |
| SCHEMBL8048673 | 0.82 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1EIF4E | |
| SCHEMBL8043968 | 0.78 | MEN1 (0.45) | MEN1KMT2AEIF4ELMNAKDM4E | |
| SCHEMBL8050933 | 0.77 | LMNA (0.40) | MEN1KMT2ARAB9ANPC1ALOX5 | |
| SCHEMBL8715721 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2ARAB9ANPC1ALOX5 | |
| SCHEMBL8043200 | 0.76 | ALDH1A1 (0.43) | KMT2ALMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8048723 | 0.75 | VCP (0.48) | MEN1KMT2ARAB9ANPC1ALOX5 | |
| SCHEMBL8044415 | 0.74 | MAPT (0.33) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL8044888 | 0.74 | MEN1 (0.53) | MEN1KMT2ARAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |