Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.51 |
| ▸ | CFD | P00746 | 3/20 | 0.50 |
| ▸ | F11 | P03951 | 3/20 | 0.50 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.50 |
| ▸ | FOS | P01100 | 2/20 | 0.48 |
| ▸ | JUN | P05412 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27000289 | 0.87 | CFD (0.54) | L3MBTL1CXCL8CFDF11TPSB2 | |
| SCHEMBL26725046 | 0.87 | L3MBTL1 (0.64) | L3MBTL1FOSJUNADRB2ADRB1 | |
| SCHEMBL22442208 | 0.86 | L3MBTL1 (0.51) | L3MBTL1FOSJUNADRB2ADRB1 | |
| SCHEMBL4280428 | 0.84 | ADRB2 (0.49) | L3MBTL1ADRB2ADRB1CACNA1GCACNA1H | |
| SCHEMBL18050594 | 0.81 | CXCL8 (0.47) | L3MBTL1CXCL8CFDF11TPSB2 | |
| SCHEMBL1628791 | 0.81 | L3MBTL1 (0.62) | L3MBTL1CXCL8CFDF11TPSB2 | |
| Bicarbonate SCHEMBL28233771 | 0.81 | LTB4R (0.48) | FOSJUNADRB2ADRB1CACNA1G | |
| SCHEMBL10701443 | 0.80 | L3MBTL1 (0.56) | L3MBTL1ADRB2ADRB1CACNA1GCACNA1H | |
| SCHEMBL10693030 | 0.80 | ADRB2 (0.76) | ADRB2ADRB1KCNH2 | |
| SCHEMBL78090 | 0.80 | CACNA1G (0.58) | ADRB2ADRB1CACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| EP-0758013-B1 | Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display | NIPPON OIL CO LTD (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5855971-A | Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film | NIPPON OIL COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0758013-A1 | Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display | NIPPON OIL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | CGAS, GLS2, GLS | L3MBTL1 4285/4885CXCL8 1479/4885CFD 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.