Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 3/20 | 0.34 |
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697020 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL8077039 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL8085305 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AGABRA1GABRG2 | |
| SCHEMBL7277069 | 0.86 | PDE4A (0.39) | POLBTDP1HTTMALT1KDM4E | |
| SCHEMBL8088445 | 0.86 | ADORA3 (0.41) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL8085338 | 0.85 | KMT2A (0.38) | ALDH1A1MEN1KMT2ACTDSP1GABRA1 | |
| SCHEMBL8088352 | 0.85 | KDM4E (0.37) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL7268307 | 0.84 | ALDH1A1 (0.39) | ALDH1A1POLBMEN1KMT2ANR1H2 | |
| SCHEMBL8084793 | 0.84 | CFTR (0.39) | ALDH1A1POLBMEN1KMT2AHTT | |
| SCHEMBL8085141 | 0.83 | RECQL (0.44) | ALDH1A1POLBTDP1HTTMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |