SCHEMBL810034

SCHEMBL810034

CC(=O)C(C)Oc1ccc(OCC(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
TSHR P16473 1/20 0.57
ALOX15 P16050 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MAPT P10636 2/20 0.51
MAPK1 P28482 1/20 0.51
NR4A1 P22736 1/20 0.49
APEX1 P27695 1/20 0.49
FFAR1 O14842 1/20 0.49
MEN1 O00255 1/20 0.47
PTPN7 P35236 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN12 Q05209 1/20 0.47
PPARD Q03181 1/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HTT P42858 1/20 0.45
MCL1 Q07820 1/20 0.45
CYP1A2 P05177 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810044 0.86 ALDH1A1 (0.43) ALDH1A1TSHRSMN1; SMN2MAPTMAPK1
SCHEMBL2365252 0.81 ALOX15 (0.67) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL809955 0.80 PPARA (0.52) FFAR1PPARDL3MBTL1GAA
SCHEMBL809913 0.79 HTT (0.46) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL9856115 0.79 ALDH1A1 (0.66) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL9856122 0.79 ALDH1A1 (0.66) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL339492 0.79 ALOX15 (0.81) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL10732880 0.79 LMNA (0.72) NR4A1FFAR1LMNAL3MBTL1CYP1A2
SCHEMBL9900712 0.77 GAA (0.58) TSHRSMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL19725364 0.77 GAA (0.58) TSHRSMN1; SMN2MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM DDT, ACMSD, HPD ALDH1A1 935/4885TSHR 3202/4885ALOX15 796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.