Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107634 | 0.96 | PKM (0.37) | PKMPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8103441 | 0.90 | KDM4E (0.38) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPK1 | |
| SCHEMBL8101320 | 0.87 | CYP2D6 (0.40) | POLBALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL8101553 | 0.86 | GAA (0.38) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPK1 | |
| SCHEMBL8101312 | 0.84 | HTR1A (0.39) | POLBALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL8101881 | 0.82 | ALDH1A1 (0.43) | POLBALDH1A1CYP1A2MAPK1MAPT | |
| SCHEMBL8107632 | 0.79 | ADRA2A (0.36) | POLBALDH1A1CYP1A2MAPK1MAPT | |
| SCHEMBL8101315 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPK1MAPTALDH2ALDH3A1 | |
| SCHEMBL8103457 | 0.77 | ALDH1A1 (0.44) | POLBALDH1A1CYP1A2MAPK1MAPT | |
| SCHEMBL8103233 | 0.77 | KDM4E (0.40) | POLBALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |