Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101553 | 0.95 | GAA (0.38) | KDM4EGAAALDH1A1LMNAGLA | |
| SCHEMBL8101460 | 0.90 | PKM (0.36) | KDM4EGAAALDH1A1MAPTALDH2 | |
| SCHEMBL8107634 | 0.86 | PKM (0.37) | KDM4EGAAALDH1A1LMNANPSR1 | |
| SCHEMBL8103181 | 0.85 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNANPSR1MAPT | |
| SCHEMBL8093559 | 0.80 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNANPSR1MAPT | |
| SCHEMBL8101320 | 0.77 | CYP2D6 (0.40) | KDM4EALDH1A1LMNANPSR1MAPT | |
| SCHEMBL8101367 | 0.73 | ALDH1A1 (0.37) | ALDH1A1LMNAAPOBEC3GPTGS1PTGS2 | |
| SCHEMBL8101317 | 0.73 | KDM4E (0.47) | KDM4EGAAALDH1A1LMNAAPOBEC3G | |
| SCHEMBL8101312 | 0.72 | HTR1A (0.39) | KDM4EALDH1A1LMNANPSR1MAPT | |
| SCHEMBL1862772 | 0.69 | ALDH1A1 (0.47) | GAAALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |