Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155669 | 0.80 | LMNA (0.47) | KMT2AKCNH2MAPTGAALMNA | |
| SCHEMBL8154751 | 0.78 | KCNH2 (0.50) | KMT2AKCNH2MAPTLMNATP53 | |
| SCHEMBL8149813 | 0.77 | KCNH2 (0.44) | KMT2AMAPK1KCNH2ALDH1A1MAPT | |
| SCHEMBL8105863 | 0.74 | ALDH1A1 (0.46) | KMT2AMAPK1KCNH2HTTSMN1; SMN2 | |
| SCHEMBL8109646 | 0.74 | MGLL (0.43) | KMT2AMAPTLMNATP53L3MBTL1 | |
| SCHEMBL8096311 | 0.70 | MGLL (0.42) | KMT2AMAPTLMNATP53L3MBTL1 | |
| SCHEMBL4673293 | 0.68 | SLC18A3 (0.55) | KMT2AFNTAFNTBMAPK1SLC18A3 | |
| SCHEMBL4673290 | 0.67 | ACKR3 (0.48) | FNTAFNTBCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL13391389 | 0.67 | TACR3 (0.53) | FNTAFNTBMAPK1SLC18A3ACKR3 | |
| SCHEMBL6201576 | 0.65 | L3MBTL1 (0.65) | KMT2AFNTAFNTBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |