Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105863 | 0.85 | ALDH1A1 (0.46) | KCNH2MGLLKMT2AMEN1MAPT | |
| SCHEMBL8154751 | 0.82 | KCNH2 (0.50) | KCNH2MGLLKMT2AMEN1MAPT | |
| SCHEMBL8155669 | 0.80 | LMNA (0.47) | KCNH2MGLLKMT2AMEN1MAPT | |
| SCHEMBL8105639 | 0.77 | KMT2A (0.43) | KCNH2KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL8109646 | 0.71 | MGLL (0.43) | MGLLKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8096311 | 0.70 | MGLL (0.42) | MGLLKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8149814 | 0.68 | HTR2A (0.58) | KCNH2MGLLKMT2AMEN1DRD2 | |
| SCHEMBL8557472 | 0.65 | KMT2A (0.50) | KCNH2MGLLKMT2AMEN1MAPT | |
| SCHEMBL2297101 | 0.64 | MGLL (0.58) | MGLLKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL11849959 | 0.63 | L3MBTL1 (0.62) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |