Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16200053 | 0.80 | SLC34A1 (0.44) | SLC34A1MAPTSMN1; SMN2 | |
| SCHEMBL16200199 | 0.78 | MEN1 (0.43) | SLC34A1CHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL14039900 | 0.78 | ALDH1A1 (0.50) | SLC34A1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16200054 | 0.78 | P2RX7 (0.45) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16200057 | 0.77 | MAPK14 (0.42) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL14039556 | 0.77 | NT5E (0.41) | KDM4EALDH1A1NOTUMCYP1A2CYP11B2 | |
| SCHEMBL16200062 | 0.77 | PTGS2 (0.46) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8101768 | 0.76 | CHRNB2 (0.42) | CHRNB2CHRNA4KDM4EALDH1A1MEN1 | |
| SCHEMBL28836859 | 0.75 | AKR1C3 (0.40) | CHRNB2CHRNA4ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL7687069 | 0.73 | P2RX7 (0.37) | SLC34A1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1257490-A | Substituted pyridylpyrazoles as herbicides, insecticides and acaricides | BAYER AG (DE) | 2000-06-21 | — | — | CN | disclosed |
| EP-0983261-A1 | SUBSTITUTED PYRIDYLPYRAZOLES AS HERBICIDES, INSECTICIDES AND ACARICIDES | Bayer Aktiengesellschaft (DE) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052938-A1 | SUBSTITUTED PYRIDYLPYRAZOLES AS HERBICIDES, INSECTICIDES AND ACARICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |