SCHEMBL812697

SCHEMBL812697

Cc1ccc(C)c2nccnc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.50
CCR8 P51685 5/20 0.50
CCR5 P51681 4/20 0.50
LMNA P02545 2/20 0.44
PSMD14 O00487 2/20 0.43
COPS5 Q92905 2/20 0.43
HTT P42858 2/20 0.43
SLC6A2 P23975 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
HSP90AA1 P07900 2/20 0.42
NPC1 O15118 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HTR1A P08908 1/20 0.39
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
NOS3 P29474 3/20 0.36
NOS2 P35228 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL675712 0.89 CCR1 (0.42) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL12203219 0.87 CCR1 (0.65) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL18544788 0.84 CCR1 (0.39) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL18980173 0.84 CCR1 (0.39) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL12542981 0.83 PSMD14 (0.38) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL12542980 0.83 PSMD14 (0.38) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL19864754 0.81 PSMD14 (0.37) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL15604065 0.81 CCR1 (0.37) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL17794103 0.81 NOS3 (0.39) CCR1CCR8CCR5LMNAPSMD14
SCHEMBL3152093 0.81 MEN1 (0.44) CCR1CCR8CCR5LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657499-B1 Vulcanizable epichlorohydrin polymer composition DAISO CO LTD (JP) 1998-07-08 EP claimed
US-12631986-B2 Charging roll for electrophotographic apparatus SUMITOMO RIKO COMPANY LIMITED (JP) 2026-05-19 US disclosed
US-12590653-B2 Fuel hose SUMITOMO RIKO COMPANY LIMITED (JP) 2026-03-31 US disclosed
US-12578667-B2 Charging roll for electrophotographic machine SUMITOMO RIKO COMPANY LIMITED (JP) 2026-03-17 US disclosed
EP-4685196-A1 NEAR-INFRARED-TRANSMITTING BLACK PARTICLES, INK, AND MOLDED BODY Sekisui Chemical Co., Ltd. (JP) 2026-01-28 EP disclosed
US-12461464-B2 Charging roll for electrophotographic equipment SUMITOMO RIKO COMPANY LIMITED (JP) 2025-11-04 US disclosed
US-20250196476-A1 COMPOSITION FOR VULCANIZATION BONDING, COMPOSITIONS FOR VULCANIZATION-BONDED LAMINATE, AND LAMINATE OBTAINED FROM SAID COMPOSITIONS OSAKA SODA CO., LTD. (JP) 2025-06-19 US disclosed
EP-4567520-A1 CHARGING ROLL FOR ELECTROPHOTOGRAPHIC APPARATUS Sumitomo Riko Company Limited (JP) 2025-06-11 EP disclosed
EP-3572464-B1 COMPOSITION FOR LAMINATE OSAKA SODA CO LTD (JP) 2025-06-04 EP disclosed
US-20250147446-A1 CHARGING ROLL FOR ELECTROPHOTOGRAPHIC MACHINE SUMITOMO RIKO COMPANY LIMITED (JP) 2025-05-08 US disclosed
US-20070228359-A1 Novel Diketopyrrolopyrrole Polymers CLAP CO., LTD. (KR) 2007-10-04 US disclosed
US-20070164257-A1 Organic electroluminescent display device and chemical compounds for liquid crystals TOHOKU PIONEER CORPORATION 2007-07-19 US disclosed
WO-2007065678-A1 NOVEL MATERIALS FOR ORGANIC ELECTROLUMINIESCENT DEVICES MERCK PATENT GMBH (DE) 2007-06-14 WO disclosed
US-7220819-B2 Electroluminescent conjugated polymers containing phosphorescent moieties and the application thereof in LED NATIONAL TSING HUA UNIVERSITY (TW) 2007-05-22 US disclosed
US-7220819-B2 Electroluminescent conjugated polymers containing phosphorescent moieties and the application thereof in LED NATIONAL TSING HUA UNIVERSITY (TW) 2007-05-22 US disclosed
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon DOW GLOBAL TECHNOLOGIES INC. 2007-05-10 US disclosed
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon DOW GLOBAL TECHNOLOGIES INC. 2007-05-10 US disclosed
US-7195826-B2 Charge transfer compounds; containing organiridium compound TOHOKU PIONEER CORPORATION (JP) 2007-03-27 US disclosed
US-20070010672-A1 Fluorescent diketopyrrolopyrroles CLAP CO., LTD. (KR) 2007-01-11 US disclosed
US-20070010672-A1 Fluorescent diketopyrrolopyrroles CLAP CO., LTD. (KR) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12578667-B2 Charging roll for electrophotographic machine SELPLG, CD4, PWWP2B CCR1 618/4885CCR8 1699/4885CCR5 1695/4885
US-12590653-B2 Fuel hose HAO2, HOGA1, FGB CCR1 2228/4885CCR8 2541/4885CCR5 3702/4885
US-12631986-B2 Charging roll for electrophotographic apparatus SELE, DNAJC10, SLC9A3 CCR1 1991/4885CCR8 2920/4885CCR5 3713/4885
US-20070102695-A1 Crosslinkable substituted fluorene compounds and conjugated oligomers or polymers based thereon THEM6, PCNA, PARG CCR1 4380/4885CCR8 3318/4885CCR5 4335/4885
US-20070010672-A1 Fluorescent diketopyrrolopyrroles TYR, QDPR, MC1R CCR1 4766/4885CCR8 4864/4885CCR5 4446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.