Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293486 | 0.84 | MAOA (0.49) | LDHAMAOAEGLN1KDM4EGPR3 | |
| SCHEMBL15631107 | 0.80 | MAOA (0.49) | LDHAMAOAEGLN1KDM4EGPR3 | |
| SCHEMBL28007224 | 0.80 | MAOA (0.52) | MAOAEGLN1ALDH1A1MAPTKDM4E | |
| SCHEMBL27651389 | 0.79 | LMNA (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4EGPR3 | |
| SCHEMBL821293 | 0.78 | EGLN1 (0.68) | EGLN1EGLN2 | |
| SCHEMBL31501044 | 0.78 | EGLN1 (0.68) | EGLN1EGLN2 | |
| SCHEMBL29726498 | 0.77 | EGLN1 (0.70) | EGLN1EGLN2 | |
| SCHEMBL21361727 | 0.77 | EGLN1 (0.70) | EGLN1EGLN2 | |
| SCHEMBL25106669 | 0.76 | CTRC (0.42) | EGLN1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6718692 | 0.76 | DHODH (0.42) | EGLN1ALDH1A1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213569-A1 | METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY | NEW YORK UNIVERSITY (US) | 2025-07-03 | — | — | US | disclosed |
| WO-2024155884-A1 | HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |
| CN-104470899-B | The 4 isoquinolinol compounds as HIF hydroxylase inhibitors | 菲布罗根有限公司 | 2017-12-26 | — | — | CN | disclosed |
| CN-1117079-C | Substituted isoquinoline-3-formamides compounds, its preparing method and its use as medicine | FIBRE GENE INC (US) | 2003-08-06 | — | — | CN | disclosed |
| US-6093730-A | AN ENZYME INHIBITORS OF PROLYL-4-HYDROXYLASE FOR TREATING FIBROTIC DISORDERS AND INHIBITING COLLAGEN BIOSYNTHESIS | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 2000-07-25 | — | — | US | disclosed |
| CN-1218802-A | Substituted isoquinoline-3-formamides compounds, its preparing method and its use as medicine | HOECHST MARION ROUSSEL CO LTD (DE) | 1999-06-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250213569-A1 | METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY | DCLRE1B, RNASE1, ADAR | LDHA 1650/4885MAOA 457/4885EGLN1 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.