SCHEMBL816786

SCHEMBL816786

OCc1cc(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.44
ACHE P22303 1/20 0.39
RXRA P19793 2/20 0.38
RXRB P28702 2/20 0.38
RXRG P48443 2/20 0.38
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
S1PR1 P21453 2/20 0.33
PRKCA P17252 1/20 0.33
PRKCD Q05655 1/20 0.33
IDO1 P14902 2/20 0.32
NOTUM Q6P988 1/20 0.31
AR P10275 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CASP6 P55212 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3317064 0.79 KIF11 (0.43) KIF11ACHERXRARXRBRXRG
SCHEMBL14304179 0.76 IDO1 (0.32) IDO1
SCHEMBL816857 0.76 LOXL2 (0.39) HTR2AHTR2CIDO1KDM4E
SCHEMBL21490278 0.76 KIF11 (0.36) KIF11NOTUM
SCHEMBL5251030 0.76 IDO1 (0.32) IDO1
SCHEMBL17284128 0.76 KIF11 (0.44) KIF11ACHERXRARXRBRXRG
SCHEMBL5251032 0.76 HSPA5 (0.38) RXRARXRBHTR2AHTR2CHTR2B
SCHEMBL816314 0.76 IDO1 (0.32) IDO1
SCHEMBL24852184 0.76 KIF11 (0.49) KIF11ACHERXRARXRBRXRG
SCHEMBL6865891 0.76 RXRA (0.39) RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4484407-A2 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2025-01-01 EP disclosed
CN-116082563-B (Meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2024-09-20 CN disclosed
CN-118359760-A Optical resin, optical element, and optical device 株式会社 尼康 2024-07-19 CN disclosed
US-20230382775-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2023-11-30 US disclosed
US-20230382775-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2023-11-30 US disclosed
US-11772997-B2 Method for extracting salts and temperature-regenerated extracting composition ADIONICS (FR) 2023-10-03 US disclosed
US-11772997-B2 Method for extracting salts and temperature-regenerated extracting composition ADIONICS (FR) 2023-10-03 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
CN-116082563-A (meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2023-05-09 CN disclosed
US-8049022-B2 Fluorosurfactants MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-11-01 US disclosed
US-8049022-B2 Fluorosurfactants MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-11-01 US disclosed
US-20100152081-A1 Fluorosurfactants MERCK PATENT GMBH (DE) 2010-06-17 US disclosed
US-20100152081-A1 Fluorosurfactants MERCK PATENT GMBH (DE) 2010-06-17 US disclosed
US-20090312432-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT (DE) 2009-12-17 US disclosed
US-20090312432-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT (DE) 2009-12-17 US disclosed
US-20090264525-A1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2009-10-22 US disclosed
US-20090264525-A1 FLUOROSURFACTANTS MERCK PATENT GMBH (DE) 2009-10-22 US disclosed
US-20090197201-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT (DE) 2009-08-06 US disclosed
US-20090197201-A1 FLUOROSURFACTANTS MERCK PATENT GESELLSCHAFT (DE) 2009-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 KIF11 1800/4885ACHE 647/4885RXRA 1493/4885
US-20090312432-A1 FLUOROSURFACTANTS SGMS2, FASN, SGMS1 KIF11 4306/4885ACHE 4091/4885RXRA 441/4885
US-20100152081-A1 Fluorosurfactants CBR3, FPR3, NOX3 KIF11 3333/4885ACHE 3673/4885RXRA 1426/4885
US-20090264525-A1 FLUOROSURFACTANTS FASN, FFAR3, SGMS2 KIF11 4154/4885ACHE 4537/4885RXRA 559/4885
US-20090197201-A1 FLUOROSURFACTANTS CBR3, SCO2, FPR3 KIF11 3312/4885ACHE 3633/4885RXRA 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.