Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221280 | 0.94 | MEN1 (0.33) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4730340 | 0.86 | HPGD (0.41) | HPGDSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL8213322 | 0.84 | PDGFRB (0.42) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8221266 | 0.84 | RAB9A (0.49) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8214695 | 0.82 | ALDH1A1 (0.40) | HPGDSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL8219294 | 0.81 | HPGDS (0.41) | SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL4730660 | 0.80 | SMN1; SMN2 (0.41) | HPGDSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL8268378 | 0.77 | KDM4E (0.48) | HPGDSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL8219508 | 0.73 | LMNA (0.40) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8213285 | 0.72 | MAPT (0.45) | ALDH1A1KMT2APOLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |