Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 16/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214695 | 0.94 | ALDH1A1 (0.40) | HPGDSKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8213322 | 0.88 | PDGFRB (0.42) | KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL4728657 | 0.87 | HPGDS (0.46) | HPGDSKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8221266 | 0.85 | RAB9A (0.49) | KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8266779 | 0.81 | MAOB (0.44) | KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8214243 | 0.81 | HPGD (0.33) | KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8221280 | 0.81 | MEN1 (0.33) | KMT2ASMN1; SMN2 | |
| SCHEMBL8219508 | 0.81 | LMNA (0.40) | KMT2ASMN1; SMN2 | |
| SCHEMBL4731550 | 0.80 | ALDH1A1 (0.47) | KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL4729596 | 0.73 | PDGFRB (0.50) | KDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |