Sugi Predict

Sugi Predict / Compounds / SCHEMBL822567

SCHEMBL822567

SCHEMBL822567

O=COc1ccc2c3c(ccc(C(=O)NCCc4ccccc4)c13)C(=O)N(C1CCCCC1)C2=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ EPHX2 P34913 2/20 0.42
▸ CRHBP P24387 1/20 0.42
▸ CRHR2 Q13324 1/20 0.42
▸ TSHR P16473 2/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ POLB P06746 2/20 0.40
▸ NPC1 O15118 3/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ EPHX1 P07099 1/20 0.40
▸ CNR2 P34972 1/20 0.39
▸ CTSL P07711 1/20 0.39
▸ CTSS P25774 1/20 0.39
▸ CTSK P43235 1/20 0.39
▸ TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL823145 0.86 KMT2A (0.47) KMT2AMEN1ALDH1A1EPHX2TSHR
SCHEMBL822751 0.84 CNR2 (0.42) ALDH1A1POLBNPC1RAB9ASMN1; SMN2
SCHEMBL822671 0.79 ALDH1A1 (0.41) KMT2AMEN1ALDH1A1TSHRHSD17B10
SCHEMBL822568 0.78 MAPT (0.44) ALDH1A1EPHX2POLBNPC1RAB9A
SCHEMBL822558 0.77 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10NPC1RAB9A
SCHEMBL822491 0.76 THRB (0.46) KMT2AMEN1POLBNPC1RAB9A
SCHEMBL822451 0.76 ALDH1A1 (0.43) KMT2AMEN1ALDH1A1POLBNPC1
SCHEMBL822452 0.74 MEN1 (0.45) KMT2AMEN1ALDH1A1POLBNPC1
SCHEMBL12102581 0.73 THRB (0.45) KMT2AMEN1ALDH1A1POLBNPC1
SCHEMBL12039531 0.69 POLB (0.49) KMT2AMEN1ALDH1A1POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 — — US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 — — US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 — — US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 — — US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC KMT2A 2050/4885MEN1 3245/4885ALDH1A1 508/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC KMT2A 1249/4885MEN1 1371/4885ALDH1A1 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.