Santin

Santin

SCHEMBL82415

COc1ccc(-c2oc3cc(O)c(OC)c(O)c3c(=O)c2OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 5/20 1.00
TUBB P07437 5/20 1.00
TUBA3C P0DPH7 5/20 1.00
TUBA1B P68363 5/20 1.00
TUBA4A P68366 5/20 1.00
TUBB4B P68371 5/20 1.00
TUBB3 Q13509 5/20 1.00
TUBB2A Q13885 5/20 1.00
TUBB8 Q3ZCM7 5/20 1.00
TUBA3E Q6PEY2 5/20 1.00
TUBA1A Q71U36 5/20 1.00
TUBA1C Q9BQE3 5/20 1.00
TUBB6 Q9BUF5 5/20 1.00
TUBB2B Q9BVA1 5/20 1.00
TUBB1 Q9H4B7 5/20 1.00
XDH P47989 2/20 1.00
MAPT P10636 2/20 1.00
PKM P14618 1/20 1.00
NR0B1 P51843 1/20 0.74
CYP3A4 P08684 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6563621 0.92 TUBB4A (0.86) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Betuletol SCHEMBL29400938 0.92 TUBB4A (0.86) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
3,6-Dimethoxy Kaempferol SCHEMBL1156264 0.91 TUBB4A (0.83) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
3,6-Dimethoxy Kaempferol SCHEMBL30707828 0.91 TUBB4A (0.83) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL5073336 0.89 ABCG2 (0.84) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL27559447 0.88 TUBB4A (0.79) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Axillarin SCHEMBL29929648 0.87 XDH (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Axillarin SCHEMBL1155670 0.87 XDH (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Axillarin SCHEMBL29929599 0.87 XDH (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL22855838 0.87 TUBB4A (0.85) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
WO-2020136240-A1 POLYPHENOL-PEPTIDE CONJUGATES FOR NUCLEAR-TARGETED DELIVERY Universität Wien (AT) 2020-07-02 WO claimed
EP-3673920-A1 POLYPHENOL-PEPTIDE CONJUGATES FOR NUCLEAR-TARGETED DELIVERY Universität Wien (AT) 2020-07-01 EP claimed
CN-122029633-A Based on electron beam pumping-detection resonance spectroscopy 维也纳工业大学 2026-05-12 CN disclosed
US-12617913-B2 Reversible wrinkle patterns and methods of making and using the same TRUSTEES OF TUFTS COLLEGE (US) 2026-05-05 US disclosed
US-12534538-B2 Anti-HER2 binding molecules Certis Therapeutics Pty Ltd (AU) 2026-01-27 US disclosed
US-20260015428-A1 TARGETING IL17 SIGNALING TO TREAT CANCER AND TO PREVENT AND TREAT ICI INDUCED IMMUNE RELATED ADVERSE EVENTS (IRAES) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2026-01-15 US disclosed
US-20260002180-A1 PLATFORM FOR BIO-BASED PRODUCTION OF HIGH LEVELS OF O-PHOSPHOSERINE, CYSTEATE, OR TAURINE NATÁUR INC. (US) 2026-01-01 US disclosed
US-20250388642-A1 COMPOSITIONS AND METHODS FOR IMPROVED NK CELL THERAPIES CERUS CORPORATION (US) 2025-12-25 US disclosed
US-20250382622-A1 METHODS FOR PREVENTION, DELAY OF PROGRESSION OR TREATMENT OF CHOLESTASIS AND/OR FIBROSIS ASSOCIATED WITH CHOLESTASIS UNIV BERN (CH) 2025-12-18 US disclosed
EP-4200649-B1 SYSTEMS FOR COINCIDENCE DETECTION IN X-RAY DETECTORS GE PREC HEALTHCARE LLC (US) 2025-12-10 EP disclosed
CN-1237909-A Cancer immunotherapy using tumor cells in combination with mixed lymphocytes UNIV CALIFORNIA (US) 1999-12-08 CN disclosed
EP-0930887-A2 CANCER IMMUNOTHERAPY USING TUMOR CELLS COMBINED WITH MIXED LYMPHOCYTES The Regents of the University of California (US) 1999-07-28 EP disclosed
EP-0915708-A1 CANCER IMMUNOTHERAPY USING AUTOLOGOUS TUMOR CELLS COMBINED WITH ALLOGENEIC CYTOKINE-SECRETING CELLS The Regents of the University of California (US) 1999-05-19 EP disclosed
WO-1998016238-A2 CANCER IMMUNOTHERAPY USING TUMOR CELLS COMBINED WITH MIXED LYMPHOCYTES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-23 WO disclosed
WO-1998004282-A1 CANCER IMMUNOTHERAPY USING AUTOLOGOUS TUMOR CELLS COMBINED WITH ALLOGENEIC CYTOKINE-SECRETING CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-02-05 WO disclosed
EP-0813209-A2 Method for erasing non-volatile memory TEXAS INSTRUMENTS INCORPORATED (US) 1997-12-17 EP disclosed
US-5636162-A FOR ERASING A NONVOLATILE MEMORY ARRAY TEXAS INSTRUMENTS INCORPORATED (US) 1997-06-03 US disclosed
US-5357463-A Method for reverse programming of a flash EEPROM MICRON SEMICONDUCTOR, INC. (US) 1994-10-18 US disclosed
WO-1989002590-A1 ENHANCED SYSTEM FOR TRANSMISSION LOSS COMPARISON CIRCUITS AND SYSTEMS INC. (US) 1989-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617913-B2 Reversible wrinkle patterns and methods of making and using the same CUTA, TTN, MYOF TUBB4A 1457/4885TUBB 1121/4885TUBA3C 1762/4885
US-20260002180-A1 PLATFORM FOR BIO-BASED PRODUCTION OF HIGH LEVELS OF O-PHOSPHOSERINE, CYSTEATE, OR TAURINE UROD, DDC, CBS TUBB4A 1881/4885TUBB 447/4885TUBA3C 1078/4885
US-20250388642-A1 COMPOSITIONS AND METHODS FOR IMPROVED NK CELL THERAPIES KLRK1, MICA, PBK TUBB4A 3729/4885TUBB 3599/4885TUBA3C 3182/4885
US-20260015428-A1 TARGETING IL17 SIGNALING TO TREAT CANCER AND TO PREVENT AND TREAT ICI INDUCED IMMUNE RELATED ADVERSE EVENTS (IRAES) CD274, PDCD1, PDCD1LG2 TUBB4A 3372/4885TUBB 3694/4885TUBA3C 4047/4885
US-12534538-B2 Anti-HER2 binding molecules IGSF11, ERBB2, IGLV6-57 TUBB4A 2320/4885TUBB 1590/4885TUBA3C 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.