Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256849 | 0.86 | PARP1 (0.34) | HTR1AHTR7CDK2CDK9MAPT | |
| SCHEMBL8257859 | 0.86 | SCN9A (0.40) | HTR1AHTR7TRPM8THRBDRD2 | |
| SCHEMBL8258997 | 0.85 | HTR1A (0.38) | HTR1AHTR7CDK2CDK9 | |
| SCHEMBL8258142 | 0.79 | XDH (0.35) | TRPM8CDK2CDK9 | |
| SCHEMBL8259066 | 0.79 | ALDH1A1 (0.36) | HTR7DRD2MAPT | |
| SCHEMBL8248843 | 0.77 | LMNA (0.36) | HTR1ACDK2CDK9MAPT | |
| SCHEMBL8254298 | 0.76 | DRD2 (0.35) | HTR1AHTR7DRD2CDK2CDK9 | |
| SCHEMBL8258120 | 0.75 | CNR2 (0.36) | FABP3FABP4CDK2CDK9SCN9A | |
| SCHEMBL8211899 | 0.73 | NFKB1 (0.41) | HTR1AHTR7TRPM8THRBDRD2 | |
| SCHEMBL8248817 | 0.72 | AQP1 (0.38) | HTR1AHTR7TRPM8MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116165-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |