Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31492069 | 0.84 | AHR (0.47) | AHRFFAR1GPR84HTR1BPIK3CD | |
| SCHEMBL3730120 | 0.84 | AHR (0.47) | AHRFFAR1GPR84HTR1BPIK3CD | |
| SCHEMBL6902688 | 0.84 | AHR (0.47) | AHRFFAR1GPR84HTR1BPIK3CD | |
| SCHEMBL15596497 | 0.83 | PIK3CD (0.47) | AHRFFAR1GPR84HTR1BPIK3CD | |
| SCHEMBL3793641 | 0.81 | GPR84 (0.46) | AHRFFAR1GPR84HTR1BHTR2C | |
| SCHEMBL6099297 | 0.78 | PTGS2 (0.42) | AHRHTR1BKDM4E | |
| SCHEMBL29966571 | 0.78 | PTGS2 (0.42) | AHRHTR1BKDM4E | |
| SCHEMBL29777154 | 0.77 | HTR6 (0.43) | AHRFFAR1GPR84HTR1BPIK3CD | |
| SCHEMBL5150779 | 0.77 | AHR (0.41) | AHRFFAR1GPR84HTR1BPIK3CD | |
| SCHEMBL10372813 | 0.77 | HTR6 (0.43) | AHRFFAR1GPR84HTR1BPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046774-A | Process for N-phosphorylation of heterocyclic amines | MOBIL OIL CORPORATION (US) | 1977-09-06 | — | — | US | claimed |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240208967-A1 | Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof | INVENTISBIO CO LTD (CN) | 2024-06-27 | — | — | US | disclosed |
| EP-3790886-B1 | KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024026540-A1 | INHIBITORS AND USES THEREFOR | MACQUARIE UNIVERSITY (AU) | 2024-02-08 | — | — | WO | disclosed |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20240025918-A1 | KRAS G12D Inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-01-25 | — | — | US | disclosed |
| US-20240025918-A1 | KRAS G12D Inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-01-25 | — | — | US | disclosed |
| US-7202247-B2 | 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders | ATHEROGENICS, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202247-B2 | 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders | ATHEROGENICS, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-7115751-B2 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI RAYON CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20060211793-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI RAYONE CO., LTD. (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20060052509-A1 | Composition containing carbon nanotubes having coating thereof and process for producing them | MITSUBISHI RAYON CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1481978-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | Mitsubishi Rayon Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040019097-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| EP-1327632-A1 | METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF | Mitsubishi Rayon Co., Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208967-A1 | Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof | EGFR, WEE1, DPYD | AHR 1196/4885FFAR1 203/4885GPR84 1830/4885 |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | PIN4, IPO5, HLCS | AHR 67/4885FFAR1 2474/4885GPR84 2397/4885 |
| US-20060211793-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | IDO1, IDO2, INMT | AHR 60/4885FFAR1 4502/4885GPR84 4150/4885 |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | PDXK, HIPK1, PCK1 | AHR 3059/4885FFAR1 2934/4885GPR84 1417/4885 |
| US-20040019097-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | IDO1, IDO2, INMT | AHR 51/4885FFAR1 4577/4885GPR84 4312/4885 |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | AHR 3063/4885FFAR1 4554/4885GPR84 4082/4885 |
| US-20240025918-A1 | KRAS G12D Inhibitors | KRAS, NRAS, HRAS | AHR 732/4885FFAR1 3596/4885GPR84 3460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.