Thiosulfuric Acid

Thiosulfuric Acid

SCHEMBL828950

O=S([O-])([O-])=S.O=S([O-])([O-])=S.O=S([O-])([O-])=S.[Au+3].[Na+].[Na+].[Na+]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Thiosulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiosulfuric Acid SCHEMBL146659 1.00 MEN1 (0.46) MEN1ALDH1A1TSHRKMT2AKDM4E
Thiosulfuric Acid SCHEMBL31090016 1.00
Thiosulfuric Acid SCHEMBL28476703 0.95 MEN1 (0.43) MEN1ALDH1A1TSHRKMT2AKDM4E
Thiosulfuric Acid SCHEMBL896433 0.95 MEN1 (0.43) MEN1ALDH1A1TSHRKMT2AKDM4E
Thiosulfuric Acid SCHEMBL11787332 0.95 ALDH1A1 (0.50) MEN1ALDH1A1TSHRKMT2AKDM4E
Thiosulfuric Acid SCHEMBL4088 0.95
Thiosulfuric Acid SCHEMBL27724216 0.95 ALDH1A1 (0.50) MEN1ALDH1A1TSHRKMT2AKDM4E
Thiosulfuric Acid SCHEMBL11200821 0.95 ALDH1A1 (0.50) MEN1ALDH1A1TSHRKMT2AKDM4E
Thiosulfuric Acid SCHEMBL337690 0.95 MEN1 (0.39) MEN1ALDH1A1TSHRKMT2A
Thiosulfuric Acid SCHEMBL7156513 0.90 MEN1 (0.36) MEN1ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3186413-B1 COMPOSITION, USE THEREOF AND METHOD FOR ELECTRODEPOSITING GOLD CONTAINING LAYERS ATOTECH DEUTSCHLAND GMBH (DE) 2019-02-06 EP disclosed
EP-3023520-B1 ENVIRONMENTALLY FRIENDLY GOLD ELECTROPLATING COMPOSITIONS AND CORRESPONDING METHOD ROHM & HAAS ELECT MAT (US) 2019-01-30 EP disclosed
EP-1306466-B1 Electroless gold plating composition ROHM & HAAS ELECT MAT (US) 2018-11-21 EP disclosed
EP-2634293-B1 COMPOSITES OF CARBON BLACK AND METAL ROHM & HAAS ELECT MAT (US) 2018-07-18 EP disclosed
EP-3186413-A1 COMPOSITION, USE THEREOF AND METHOD FOR ELECTRODEPOSITING GOLD CONTAINING LAYERS ATOTECH Deutschland GmbH (DE) 2017-07-05 EP disclosed
US-20170159195-A1 COMPOSITION, USE THEREOF AND METHOD FOR ELECTRODEPOSITING GOLD CONTAINING LAYERS ATOTECH DEUTSCHLAND GMBH (DE) 2017-06-08 US disclosed
EP-1728898-B1 Electrolytes for the deposition of gold alloys ROHM & HAAS ELECT MAT (US) 2017-02-22 EP disclosed
US-20160145756-A1 ENVIRONMENTALLY FRIENDLY GOLD ELECTROPLATING COMPOSITIONS AND METHODS ROHM AND HAAS ELECRONIC MATERIALS LLC 2016-05-26 US disclosed
US-20160145745-A1 FORMALDEHYDE-FREE ELECTROLESS METAL PLATING COMPOSITIONS AND METHODS ROHM AND HAAS ELECRONIC MATERIALS LLC 2016-05-26 US disclosed
EP-3023515-A2 FORMALDEHYDE-FREE ELECTROLESS METAL PLATING COMPOSITIONS AND METHODS Rohm and Haas Electronic Materials LLC (US) 2016-05-25 EP disclosed
US-20090104463-A1 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC 2009-04-23 US disclosed
US-7465385-B2 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2008-12-16 US disclosed
US-20060283714-A1 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2006-12-21 US disclosed
EP-1728898-A2 Electrolytes for the deposition of gold alloys Rohm and Haas Electronic Materials LLC (US) 2006-12-06 EP disclosed
US-6911230-B2 Plating method SHIPLEY COMPANY, L.L.C. (US) 2005-06-28 US disclosed
US-6776828-B2 ELECTROLESS GOLD PLATING COMPOSITION COMPRISING ONE OR MORE WATER SOLUBLE GOLD COMPOUNDS, ONE OR MORE GOLD COMPLEXING AGENTS, ONE OR MORE ORGANIC STABILIZER COMPOUNDS, AND ONE OR MORE UNIFORMITY ENHANCERS SHIPLEY COMPANY, L.L.C. 2004-08-17 US disclosed
US-20040018308-A1 Plating method SHIPLEY COMPANY, L.L.C. 2004-01-29 US disclosed
US-20040009292-A1 Including one or more water soluble gold compounds, gold complexing agents, organic stabilizer compounds, and carboxylic acid uniformity enhancers; for printed wiring board substrates, integrated circuits, lead frames, pads SHIPLEY COMPANY, L.L.C. (US) 2004-01-15 US disclosed
EP-1319734-A1 Plating method Shipley Co. L.L.C. (US) 2003-06-18 EP disclosed
EP-1306466-A2 Electroless gold plating composition Shipley Co. L.L.C. (US) 2003-05-02 EP disclosed