Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21701241 | 0.88 | NOTUM (0.34) | NOTUM | |
| SCHEMBL12535480 | 0.86 | GABRB3 (0.40) | NOTUMGABRB3CES2MAPTRAPGEF4 | |
| SCHEMBL3190814 | 0.84 | CES2 (0.40) | NOTUMCES2MAPTRAPGEF4CACNA1H | |
| SCHEMBL10104516 | 0.82 | RAPGEF4 (0.38) | NOTUMGABRB3CES2MAPTRAPGEF4 | |
| SCHEMBL10104495 | 0.80 | HTT (0.37) | NOTUMMAPTNPSR1RAPGEF4ALDH1A1 | |
| SCHEMBL13550134 | 0.79 | RAPGEF4 (0.39) | NOTUMCES2RAPGEF4CACNA1HCACNA1C | |
| SCHEMBL22866837 | 0.78 | NOTUM (0.36) | NOTUMMAPTNPSR1MEN1KMT2A | |
| SCHEMBL5734053 | 0.78 | GABRB3 (0.36) | NOTUMGABRB3CES2RAPGEF4RIPK1 | |
| SCHEMBL29560549 | 0.78 | NOTUM (0.36) | NOTUMMAPTNPSR1MEN1KMT2A | |
| SCHEMBL5667400 | 0.77 | CES2 (0.36) | NOTUMGABRB3CES2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099807-B1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSEONICS INC (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2099807-B1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSEONICS INC (US) | 2014-01-01 | — | — | EP | disclosed |
| US-8143068-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-7851225-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | NOTUM 3852/4885GABRB3 2499/4885CES2 4067/4885 |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | AOX1, GPX4, SQOR | NOTUM 1626/4885GABRB3 482/4885CES2 381/4885 |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | AOX1, GPX4, SQOR | NOTUM 1626/4885GABRB3 482/4885CES2 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.