SCHEMBL829566

SCHEMBL829566

Cc1nc[nH]c1C(=S)[S-].[Na+]

nearest known ligand 0.33

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GDA Q9Y2T3 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
QPCT Q16769 1/20 0.31
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4353332 0.77
SCHEMBL828958 0.77
SCHEMBL11260169 0.72 KDM4E (0.33) KDM4E
Hydrochloric Acid SCHEMBL11400013 0.68 TDP1 (0.40) KDM4EGDAGAATDP1L3MBTL1
SCHEMBL11507885 0.68
Hydrochloric Acid SCHEMBL947740 0.68 KDM4E (0.47) MAPTKDM4EGDASMN1; SMN2GAA
SCHEMBL11191356 0.68
SCHEMBL677524 0.66
SCHEMBL11194332 0.66
Bromide SCHEMBL7030389 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1728898-B1 Electrolytes for the deposition of gold alloys ROHM & HAAS ELECT MAT (US) 2017-02-22 EP disclosed
US-8142637-B2 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-03-27 US disclosed
US-20090104463-A1 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC 2009-04-23 US disclosed
US-7465385-B2 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2008-12-16 US disclosed
US-20060283714-A1 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2006-12-21 US disclosed
EP-1728898-A2 Electrolytes for the deposition of gold alloys Rohm and Haas Electronic Materials LLC (US) 2006-12-06 EP disclosed
EP-0069443-B1 IMIDAZOLES, THEIR PRODUCTION AND THEIR USE IN PREVENTING CORROSION OF SILVER SHIKOKU CHEMICALS CORPORATION (JP) 1984-11-07 EP disclosed
US-4469622-A Method for preventing rusting in silver by using novel imidazole-4(5)-dithiocarboxylic acids in organic solvent SHIKOKU CHEMICALS CORPORATION (JP) 1984-09-04 US disclosed
US-4394511-A Imidazole 4(5)-dithiocarboxylic acids or salts SHIKOKU CHEMICALS CORPORATION (JP) 1983-07-19 US disclosed