Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634300 | 0.74 | RIPK1 (0.44) | RIPK1NR3C1KDM4ELMNA | |
| SCHEMBL6752757 | 0.74 | CYP2D6 (0.44) | NR3C1MAPTATMCYP2D6L3MBTL1 | |
| SCHEMBL2896278 | 0.74 | NR3C1 (0.47) | NR3C1ATMCYP2D6L3MBTL1SRC | |
| SCHEMBL704479 | 0.74 | L3MBTL1 (0.38) | PPARARIPK1NR3C1MAPTATM | |
| SCHEMBL29008441 | 0.72 | CYP2D6 (0.43) | NR3C1MAPTATMCYP2D6L3MBTL1 | |
| SCHEMBL585429 | 0.72 | TRPA1 (0.48) | RIPK1 | |
| SCHEMBL15006719 | 0.72 | RIPK1 (0.52) | RIPK1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL9493203 | 0.71 | LMNA (0.43) | RIPK1LMNA | |
| SCHEMBL16853358 | 0.71 | CYP2C19 (0.48) | PPARAMAPTCYP2D6 | |
| SCHEMBL707571 | 0.70 | RIPK1 (0.35) | RIPK1NR3C1ATML3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004105750-A1 | 3-AMINOMETHYL-PYRROLIDINES AS N-TYPE CALCIUM CHANNEL BLOCKERS | NEUROMED TECHNOLOGIES, INC. (CA) | 2004-12-09 | — | — | WO | disclosed |