Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309882 | 0.91 | DRD2 (0.46) | — | |
| SCHEMBL8307723 | 0.83 | DRD2 (0.32) | — | |
| SCHEMBL7516507 | 0.81 | PNMT (0.42) | — | |
| SCHEMBL7510864 | 0.80 | — | — | |
| SCHEMBL8308422 | 0.80 | ACHE (0.36) | — | |
| SCHEMBL7506577 | 0.79 | PNMT (0.44) | — | |
| SCHEMBL7512695 | 0.79 | F2 (0.31) | — | |
| SCHEMBL8309546 | 0.79 | FYN (0.47) | CA12CA1CA2 | |
| SCHEMBL7512428 | 0.78 | L3MBTL3 (0.31) | — | |
| SCHEMBL8309596 | 0.78 | SMO (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759027-B1 | BICYCLIC AMIDINE DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHETASE | ASTRA AB (SE) | 1999-08-04 | — | — | EP | claimed |