Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | SCN4A | P35499 | 5/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324378 | 0.84 | SCN4A (0.44) | SCN4A | |
| SCHEMBL8326387 | 0.83 | TAAR1 (0.41) | HTR2AKIF11 | |
| SCHEMBL8323194 | 0.82 | MAOA (0.50) | SCN4A | |
| SCHEMBL8324064 | 0.81 | SCN4A (0.44) | SCN4A | |
| SCHEMBL8321946 | 0.81 | NFE2L2 (0.49) | — | |
| SCHEMBL8326846 | 0.79 | RELA (0.46) | HTR2ASCN4A | |
| SCHEMBL8322926 | 0.77 | IDO1 (0.52) | HTR2A | |
| SCHEMBL8322751 | 0.75 | LMNA (0.37) | KIF11 | |
| SCHEMBL8322049 | 0.75 | TACR1 (0.41) | SCN4A | |
| SCHEMBL16105692 | 0.73 | AHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948496-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024780-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |