Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326437 | 0.71 | KDM4E (0.43) | KDM4EMAPTPOLB | |
| SCHEMBL8326581 | 0.70 | SPHK2 (0.34) | ALDH1A1 | |
| SCHEMBL8326577 | 0.70 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8328988 | 0.70 | KDM4E (0.31) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8327922 | 0.69 | BCHE (0.35) | ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL8327173 | 0.69 | PRKAA2 (0.42) | ALDH1A1 | |
| SCHEMBL8328991 | 0.69 | ALDH1A1 (0.31) | ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL8324755 | 0.69 | SIGMAR1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL8328371 | 0.69 | NOS3 (0.35) | — | |
| SCHEMBL8328374 | 0.69 | ACHE (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |