Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 10/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326188 | 0.93 | CYP19A1 (0.55) | CRHBPCRHR2ARPOLBCYP19A1 | |
| SCHEMBL8323939 | 0.93 | AR (0.49) | CRHBPCRHR2ARPOLBCYP19A1 | |
| SCHEMBL8327171 | 0.93 | CRHBP (0.42) | CRHBPCRHR2ARPOLBCYP19A1 | |
| SCHEMBL8327623 | 0.93 | ALDH1A1 (0.50) | CRHBPCRHR2ARPOLBCYP19A1 | |
| SCHEMBL8329070 | 0.90 | MMP1 (0.45) | CRHBPCRHR2ARPOLBCYP19A1 | |
| SCHEMBL8323517 | 0.90 | KCNJ1 (0.46) | CRHBPCRHR2ARPOLBCYP19A1 | |
| SCHEMBL8324619 | 0.90 | KCNJ1 (0.46) | CRHBPCRHR2ARPOLBCYP19A1 | |
| SCHEMBL5843018 | 0.78 | CRHBP (0.64) | CRHBPCRHR2ARALDH1A1CYP1A2 | |
| SCHEMBL8327373 | 0.77 | ALDH1A1 (0.61) | CRHBPCRHR2POLBCYP19A1ALDH1A1 | |
| SCHEMBL8327951 | 0.73 | SLC29A1 (0.41) | POLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| CN-1039228-C | Novel substituted tert-amino compund | YAMANOUCHI PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| CN-1079962-A | New substituted tertiary amine compound and salt thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1993-12-29 | — | — | CN | disclosed |