Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329548 | 0.89 | LTA4H (0.41) | PPIDLTA4HALDH1A1POLBMAPT | |
| SCHEMBL8798766 | 0.88 | CYP3A4 (0.37) | GPR119ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL8799931 | 0.85 | TSHR (0.36) | CYP17A1CYP19A1LATS1PPIDALDH1A1 | |
| SCHEMBL8800048 | 0.83 | PGR (0.35) | LTA4HALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL8798264 | 0.80 | TBXAS1 (0.37) | ALDH1A1 | |
| SCHEMBL8803294 | 0.79 | MMP8 (0.38) | LTA4HALDH1A1 | |
| SCHEMBL8799769 | 0.77 | LTA4H (0.41) | CYP17A1NAMPTCYP19A1GPR119LATS1 | |
| SCHEMBL8799648 | 0.77 | MAPK1 (0.36) | ALDH1A1MAPTPKMKMT2ATSHR | |
| SCHEMBL8799066 | 0.77 | LMNA (0.39) | LTA4HLMNA | |
| SCHEMBL8798456 | 0.76 | CYP4F2 (0.32) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |