Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | IGF2R | P11717 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542344 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521297 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521065 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521049 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521142 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521051 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521293 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521070 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL7114633 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 | |
| SCHEMBL1521141 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GAATYRMAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210207184-A1 | SYNTHESIS OF GLUCAN COMPRISING ALPHA-1,3 GLYCOSIDIC LINKAGES WITH PHOSPHORYLASE ENZYMES | NUTRITION & BIOSCIENCES USA 4 INC (US) | 2021-07-08 | — | — | US | disclosed |
| EP-3740583-A1 | SYNTHESIS OF GLUCAN COMPRISING ALPHA-1,3 GLYCOSIDIC LINKAGES WITH PHOSPHORYLASE ENZYMES | Danisco US Inc. (US) | 2020-11-25 | — | — | EP | disclosed |
| US-10808269-B2 | Synthesis of glucan comprising alpha-1,3 glycosidic linkages with phosphorylase enzymes | DANISCO US INC (US) | 2020-10-20 | — | — | US | disclosed |
| US-20190264247-A1 | SYNTHESIS OF GLUCAN COMPRISING ALPHA-1,3 GLYCOSIDIC LINKAGES WITH PHOSPHORYLASE ENZYMES | DANISCO US, INC. | 2019-08-29 | — | — | US | disclosed |
| WO-2019165060-A1 | SYNTHESIS OF GLUCAN COMPRISING ALPHA-1,3 GLYCOSIDIC LINKAGES WITH PHOSPHORYLASE ENZYMES | DANISCO US INC (US) | 2019-08-29 | — | — | WO | disclosed |
| US-5939308-A | PURE CULTURE OF BACILLUS THAT PRODUCES TREHALOSE OR GLUCOSE-1-PHOSPHORIC ACID INEXPENSIVELY AND ON INDUSTRIAL SCALE | SHOWA SANGYO CO., LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| US-5827715-A | REVERSIBLY ACTS ON MALTOSE IN PRESENCE OF PHOSPHORIC ACID TO PRODUCE GLUCOSE AND BETA-GLUCOSE 1-PHOSPHORIC ACID OR PRODUCES MALTOSE AND PHOSPHORIC ACID WHEN ACTS ON GLUCOSE AND BETA-GLUCOSE 1-PHOSPHORIC ACID | SHOWA SANGYO CO., LTD. (JP) | 1998-10-27 | — | — | US | disclosed |
| EP-0757098-A2 | Heat resistant maltose phosphorylase, process for preparation thereof, bacteria used for preparation thereof, and methods for using the enzyme | SHOWA SANGYO Co., Ltd. (JP) | 1997-02-05 | — | — | EP | disclosed |