Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.33 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358390 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNACA2GAA | |
| SCHEMBL8350665 | 0.85 | LMNA (0.51) | ALDH1A1TSHRLMNAGAAMEN1 | |
| SCHEMBL8358621 | 0.84 | CA2 (0.39) | ALDH1A1TSHRLMNACA2GAA | |
| SCHEMBL8089448 | 0.79 | LMNA (0.35) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL8354879 | 0.75 | LMNA (0.42) | ALDH1A1LMNAKDM4EHSD17B10MAPT | |
| SCHEMBL8354928 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNACA2GAA | |
| SCHEMBL8355025 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNACA2GAA | |
| SCHEMBL8358558 | 0.72 | LMNA (0.45) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL2872060 | 0.71 | LMNA (0.68) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL8088976 | 0.70 | LMNA (0.32) | TSHRLMNARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001881-A | Ortho-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | disclosed |