Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286535 | 0.91 | OPRK1 (0.45) | MAT2AGAAHPGDMAPK1GFER | |
| SCHEMBL5871913 | 0.89 | ALDH1A1 (0.42) | MAT2AGAAHPGDMAPK1HTT | |
| SCHEMBL8287944 | 0.87 | GAA (0.43) | GAAHPGDMAPK1GFERPDE11A | |
| SCHEMBL8286558 | 0.86 | PDE11A (0.46) | GAAHPGDPDE11AHTTMAPT | |
| SCHEMBL8285272 | 0.85 | PDE11A (0.37) | MAT2AGAAHPGDMAPK1PDE11A | |
| SCHEMBL8285359 | 0.84 | KDM4E (0.47) | GAAHPGDMAPK1PDE11AHTT | |
| SCHEMBL8286423 | 0.84 | KCNH3 (0.42) | MAT2AGAAHPGDMAPK1PDE11A | |
| SCHEMBL8285358 | 0.84 | GAA (0.43) | GAAHPGDGFERPDE11AHTT | |
| SCHEMBL5871645 | 0.82 | GAA (0.42) | GAAHPGDMAPK1GFERPDE11A | |
| SCHEMBL8287209 | 0.82 | PLA2G4A (0.38) | GAAHPGDMAPK1GFERPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003027112-A1 | 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |