Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801554 | 0.89 | VNN1 (0.41) | VNN1CYP11B2ALDH1A1MAPTPDE4B | |
| SCHEMBL4433475 | 0.86 | TAAR1 (0.46) | TAAR1VNN1ALDH1A1MAPK1MEN1 | |
| SCHEMBL4433472 | 0.86 | TAAR1 (0.46) | TAAR1VNN1ALDH1A1MAPK1MEN1 | |
| SCHEMBL30744688 | 0.85 | ALDH1A1 (0.47) | TAAR1VNN1ALDH1A1POLBPDE4B | |
| SCHEMBL24015942 | 0.83 | ADRA1A (0.39) | TAAR1CYP11B2CYP4A11CYP4F2ALDH1A1 | |
| SCHEMBL9794685 | 0.83 | TAAR1 (0.41) | TAAR1VNN1CYP11B2CYP4A11CYP4F2 | |
| SCHEMBL30744770 | 0.82 | VNN1 (0.43) | TAAR1VNN1ALDH1A1MAPK1POLB | |
| SCHEMBL12001420 | 0.81 | CHRNB2 (0.43) | VNN1ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL24492173 | 0.81 | BTK (0.40) | TAAR1VNN1POLB | |
| SCHEMBL18711304 | 0.81 | SPR (0.41) | TAAR1CYP11B2CYP4A11CYP4F2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210592-A1 | AMINES OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | HOFFMANN-LA ROCHE, INC. | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210592-A1 | AMINES OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | GFPT1, CEPT1, SLC18A2 | TAAR1 71/4885VNN1 2262/4885CYP11B2 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.