SCHEMBL840279

SCHEMBL840279

Cc1[c]c(C)cc(-c2cc(C)nc(C)c2)c1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
ADORA2A P29274 4/20 0.32
ADORA1 P30542 4/20 0.32
ADORA2B P29275 2/20 0.32
NOS3 P29474 2/20 0.32
NOS2 P35228 2/20 0.32
NOS1 P29475 1/20 0.32
LMNA P02545 1/20 0.31
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4852858 0.83 ALDH1A1 (0.35)
SCHEMBL1990834 0.83 POLB (0.45) POLBAPOBEC3GADORA2AADORA1ADORA2B
SCHEMBL30289670 0.80 LMNA (0.43) POLBAPOBEC3GADORA2AADORA1ADORA2B
SCHEMBL21880900 0.75 ADORA2A (0.41) POLBAPOBEC3GADORA2AADORA1ADORA2B
SCHEMBL17449879 0.72 NOS3 (0.46) POLBAPOBEC3GADORA2AADORA1ADORA2B
SCHEMBL3815899 0.72 ALDH1A1 (0.38)
SCHEMBL3819765 0.72 POLB (0.30) POLBAPOBEC3G
SCHEMBL1636770 0.70
SCHEMBL3818609 0.70 MAPT (0.52) APOBEC3GLMNA
SCHEMBL27721332 0.70 ADORA2A (0.34) POLBAPOBEC3GADORA2AADORA1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP claimed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US claimed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US claimed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US claimed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP claimed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US claimed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US claimed
US-10403832-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-09-03 US claimed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US claimed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP claimed
US-20130310561-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-f ) PHENANTHRIDINE AND DIIMIDAZO (1,2-a:1', 2'-c),QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2013-11-21 US claimed
CN-101415718-B Metal complexes of cyclometallated imidazo [1,2-f ] phenanthridine and diimidazo [1,2-a:1',2' -c ] quinazoline ligands and their isoelectronic and benzocyclo-analogs UNIVERSAL DISPLAY CORP 2013-05-29 CN claimed
EP-2399922-A1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof Universal Display Corporation (US) 2011-12-28 EP claimed
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF KNOWLES DAVID B 2011-03-31 US claimed
US-7915415-B2 Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION (US) 2011-03-29 US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP claimed
CN-101415718-A Cyclometallated imidazo [1 ] s UNIVERSAL DISPLAY CORP (US) 2009-04-22 CN claimed
EP-1981898-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZOÝ1,2-f¨PHENANTHRIDINE AND DIIMIDAZOÝ1,2-A:1',2'-C¨QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2008-10-22 EP claimed
WO-2007095118-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2007-08-23 WO claimed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF NDUFC1, CD274, CRY1 POLB 1522/4885APOBEC3G 2568/4885ADORA2A 332/4885
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 POLB 1435/4885APOBEC3G 3353/4885ADORA2A 1915/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 POLB 1412/4885APOBEC3G 1780/4885ADORA2A 1581/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 POLB 2736/4885APOBEC3G 4097/4885ADORA2A 806/4885
US-10403832-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 POLB 1692/4885APOBEC3G 2278/4885ADORA2A 4702/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 POLB 1435/4885APOBEC3G 3353/4885ADORA2A 1915/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 POLB 1435/4885APOBEC3G 3353/4885ADORA2A 1915/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 POLB 2736/4885APOBEC3G 4097/4885ADORA2A 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.