Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31107869 | 0.76 | CES2 (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL31058373 | 0.76 | VCAM1 (0.45) | KDM4ETDP1CA1CA2TSHR | |
| SCHEMBL8412750 | 0.76 | PKM (0.32) | TDP1DAOPKMPKLR | |
| SCHEMBL8412762 | 0.75 | ACHE (0.43) | KDM4EPOLBAPEX1TDP1PKM | |
| SCHEMBL3926685 | 0.75 | PKM (0.48) | TDP1PKMPKLRTSHRSMN1; SMN2 | |
| SCHEMBL29268497 | 0.75 | CA1 (0.39) | DAOPKMPKLRFABP3FABP4 | |
| SCHEMBL8412611 | 0.74 | LMNA (0.38) | TDP1DAOPKMPKLRTSHR | |
| SCHEMBL8411117 | 0.74 | PSIP1 (0.31) | — | |
| SCHEMBL2862401 | 0.72 | FABP4 (0.37) | KDM4EPOLBAPEX1TDP1FABP3 | |
| SCHEMBL10014826 | 0.72 | TET2 (0.39) | DAOTET2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |