SCHEMBL8430249

SCHEMBL8430249

CCCc1ccc(S(=O)(=O)[O-])cc1.[Na+]

nearest known ligand 0.64

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 4/20 0.64
SMN1; SMN2 Q16637 1/20 0.50
FFAR4 Q5NUL3 1/20 0.49
LMNA P02545 4/20 0.47
ALDH1A1 P00352 3/20 0.47
HTT P42858 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CNR2 P34972 1/20 0.45
NR1I2 O75469 1/20 0.45
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
KCNH2 Q12809 1/20 0.43
HIF1A Q16665 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28503721 0.88 CA2 (0.67) CA2SMN1; SMN2FFAR4LMNAALDH1A1
SCHEMBL11057835 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL2457843 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL3860078 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL149982 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL3853262 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL446403 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL11450888 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL11712823 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT
SCHEMBL11059907 0.84 CA2 (0.66) CA2SMN1; SMN2LMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115485240-B Sun-blocking compositions containing alkyl sulfonates and methods thereof 花王株式会社 2024-12-27 CN disclosed
CN-115485240-A Self-tanning compositions containing alkyl sulfonates and methods thereof 花王株式会社 2022-12-16 CN disclosed
CN-115461331-A Self-tanning composition containing aromatic sulfonate and method thereof 花王株式会社 2022-12-09 CN disclosed
EP-0748791-B1 Valine p-isopropylbenzene sulfonate and a process for purifying valine AJINOMOTO KK (JP) 1999-11-17 EP disclosed
US-5689001-A Process for purifying valine AJINOMOTO CO., INC. (JP) 1997-11-18 US disclosed
EP-0748791-A2 Valine p-isopropylbenzene sulfonate and a process for purifying valine Ajinomoto Co., Inc. (JP) 1996-12-18 EP disclosed