Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528756 | 0.77 | PARP1 (0.36) | MEN1KMT2ATDP1KDM4EMAPT | |
| SCHEMBL27732024 | 0.71 | HKDC1 (0.51) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL197980 | 0.71 | PTPN1 (0.59) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL28191302 | 0.70 | PTPN1 (0.57) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL27375220 | 0.70 | HKDC1 (0.50) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL2590035 | 0.70 | MAOA (0.48) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL28569068 | 0.68 | ALDH1A1 (0.54) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL51777 | 0.68 | ALDH1A1 (0.54) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL2380017 | 0.68 | ALDH1A1 (0.54) | MAOAMAOBHSD17B3CCR6HKDC1 | |
| SCHEMBL4585151 | 0.67 | ALOX5 (0.39) | MEN1KMT2AMAPK1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889185-A | Method of synthesizing isoindolequinones and derivatives thereof | THE UNIVERSITY OF AKRON (US) | 1999-03-30 | — | — | US | disclosed |
| WO-1998046567-A1 | METHOD OF SYNTHESIZING ISOINDOLEQUINONES AND DERIVATIVES THEREOF | THE UNIVERSITY OF AKRON (US) | 1998-10-22 | — | — | WO | disclosed |