Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 15/20 | 0.54 |
| ▸ | MMP9 | P14780 | 14/20 | 0.54 |
| ▸ | MMP1 | P03956 | 16/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559637 | 0.78 | MMP13 (0.72) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8435825 | 0.74 | MMP13 (0.45) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL7443121 | 0.73 | HTT (0.40) | MMP13MMP9MMP1MMP2MMP3 | |
| SCHEMBL6823261 | 0.72 | MMP1 (0.59) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL7378971 | 0.71 | MMP13 (0.49) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL8560568 | 0.71 | MMP9 (0.51) | MMP13MMP9MMP1MMP2 | |
| SCHEMBL6932155 | 0.70 | MMP13 (1.00) | MMP13MMP9MMP1ADAM17 | |
| SCHEMBL7552008 | 0.70 | BMP1 (0.72) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL7510525 | 0.69 | MMP13 (0.58) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6928954 | 0.68 | MMP13 (1.00) | MMP13MMP9MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863949-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 1999-01-26 | — | — | US | disclosed |