Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.32 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.32 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.32 |
| ▸ | FDPS known ✓ | P14324 | 4/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29516725 | 0.96 | LAP3 (0.37) | LAP3MMP1MMP2CA1CA2 | |
| Potassium Ion SCHEMBL29516569 | 0.96 | LAP3 (0.37) | LAP3MMP1MMP2CA1CA2 | |
| SCHEMBL406847 | 0.78 | LAP3 (0.39) | LAP3LMNAMMP1MMP2CA1 | |
| SCHEMBL28734393 | 0.77 | LAP3 (0.38) | LAP3LMNAMMP1MMP2CA1 | |
| SCHEMBL30564808 | 0.77 | LAP3 (0.38) | LAP3LMNAMMP1MMP2CA1 | |
| SCHEMBL8445268 | 0.77 | LAP3 (0.38) | LAP3LMNAMMP1MMP2CA1 | |
| Calcium SCHEMBL29918129 | 0.77 | LAP3 (0.38) | LAP3LMNAMMP1MMP2CA1 | |
| SCHEMBL16270936 | 0.70 | LAP3 (0.44) | LAP3LMNAMMP1MMP2CA1 | |
| SCHEMBL22588849 | 0.69 | LAP3 (0.42) | LAP3MMP1MMP2CA1CA2 | |
| SCHEMBL10902603 | 0.69 | LAP3 (0.42) | LAP3MMP1MMP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349138-A | Scale-inhibiting antibacterial material and preparation method thereof | 佛山市芯耀环保科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| JP-11080790-A | — | — | None | — | — | JP | disclosed |
| EP-3882346-B1 | NOVEL METALLOPROTEASES | DANISCO US INC (US) | 2025-10-01 | — | — | EP | disclosed |
| US-12091556-B2 | Stir-in titanium dioxide pigment composition | TRONOX LLC (US) | 2024-09-17 | — | — | US | disclosed |
| EP-4159854-A1 | NOVEL METALLOPROTEASES | Danisco US Inc (US) | 2023-04-05 | — | — | EP | disclosed |
| CN-114477477-B | Water treatment descaling reagent and use method and application thereof | 南京飞腾正大环保科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-3752565-B1 | STIR-IN TITANIUM DIOXIDE PIGMENT COMPOSITION | TRONOX LLC (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115069217-A | Method for preparing carbon fiber composite material and filter element | 佛山市芯耀环保科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115057542-A | Method for preparing carbon fiber composite material and filter element | 佛山市芯耀环保科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| EP-2914720-B1 | COMPOSITIONS AND METHODS COMPRISING THERMOLYSIN PROTEASE VARIANTS | DANISCO US INC (US) | 2022-08-31 | — | — | EP | disclosed |
| EP-3636662-B1 | NOVEL METALLOPROTEASES | DANISCO US INC (US) | 2022-07-13 | — | — | EP | disclosed |
| CN-111836860-B | Stirred doped titanium dioxide pigment compositions | 特罗诺克斯有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114477477-A | Water treatment descaling reagent and use method and application thereof | 南京飞腾正大环保科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114349138-A | Scale-inhibiting antibacterial material and preparation method thereof | 佛山市芯耀环保科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349106-A | Scale inhibition antibacterial activated carbon rod | 佛山市芯耀环保科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| JP-H1180790-A | DETERGENT FOR WATER SUPPLY ROLLER IN LITHO PRINTING MACHINE | FUJI PHOTO FILM CO LTD | 1999-03-26 | — | — | JP | disclosed |