SCHEMBL845562

SCHEMBL845562

c1ccc2cc3c4c(ccc3cc2c1)NNC4

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 4/20 0.39
HIF1A Q16665 2/20 0.39
CYP1B1 Q16678 1/20 0.39
GAA P10253 3/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP1A2 P05177 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
ERBB2 P04626 1/20 0.32
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
AHR P35869 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HBB P68871 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
MAPT P10636 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1159909 0.82 HSD17B10 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL4507840 0.73 ALDH1A1 (0.45) ALDH1A1HSD17B10HIF1ACYP1B1GAA
SCHEMBL31712962 0.72 HSD17B10 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL31712977 0.70 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL29532882 0.70 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1GAA
SCHEMBL4848746 0.70 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1GAA
SCHEMBL8304145 0.68 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1GAA
Cyclohexane SCHEMBL27849973 0.68 ALDH1A1 (0.62) ALDH1A1HSD17B10HIF1ACYP1B1GAA
SCHEMBL123642 0.68 HSD17B10 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL15063036 0.67 ALDH1A1 (0.68) ALDH1A1HSD17B10HIF1ACYP1B1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318652-B2 Colored speckles comprising a porous carrier and a releasing agent layer MILLIKEN & COMPANY (US) 2012-11-27 US claimed
EP-2470631-A1 COLORED SPECKLES Milliken & Company (US) 2012-07-04 EP claimed
US-20110294716-A1 Colored Speckles For Use In Granular Detergents MILLIKEN & COMPANY 2011-12-01 US claimed
WO-2011149870-A1 COLORED SPECKLES FOR USE IN GRANULAR DETERGENTS MILLIKEN & COMPANY (US) 2011-12-01 WO claimed
WO-2011028249-A1 COLORED SPECKLES MILLIKEN & COMPANY (US) 2011-03-10 WO claimed
US-20110053823-A1 Colored Speckles MILLIKEN & COMPANY 2011-03-03 US claimed
US-12042556-B2 Oxidative hair cream composition containing polymeric colorant MILLIKEN & COMPANY (US) 2024-07-23 US disclosed
US-20230270651-A1 HAIR CARE COMPOSITION CONTAINING POLYMERIC COLORANT MILLIKEN & COMPANY 2023-08-31 US disclosed
US-20230270658-A1 OXIDATIVE HAIR CREAM COMPOSITION CONTAINING POLYMERIC COLORANT MILLIKEN & COMPANY 2023-08-31 US disclosed
EP-4210657-A1 OXIDATIVE HAIR CREAM COMPOSITION CONTAINING POLYMERIC COLORANT Milliken & Company (US) 2023-07-19 EP disclosed
EP-4210835-A1 HAIR CARE COMPOSITION CONTAINING POLYMERIC COLORANT Milliken & Company (US) 2023-07-19 EP disclosed
US-11684560-B2 Oxidative hair cream composition containing polymeric colorant MILLIKEN & COMPANY (US) 2023-06-27 US disclosed
CN-116322633-A Hair care composition comprising polymeric colorant 美利肯公司 2023-06-23 CN disclosed
WO-2010065073-A2 SOLID POLYMERIC COLORANT COMPOSITIONS MILLIKEN & COMPANY (US) 2010-06-10 WO disclosed
US-20100125957-A1 Solid Polymeric Colorant Compositions HONG XIAOYONG 2010-05-27 US disclosed
EP-0215322-B1 COLORED THERMOPLASTIC RESIN COMPOSITION MILLIKEN RESEARCH CORPORATION (US) 1993-05-26 EP disclosed
US-4812141-A POLYALKYLENE OXIDE SUBSTITUTED CHROMOPHORE MILLIKEN RESEARCH CORPORATION (US) 1989-03-14 US disclosed
US-4732570-A ALKYLENEOXY SUBSTITUTED CHROMOPHORE MILLIKEN RESEARCH CORPORATION (US) 1988-03-22 US disclosed
EP-0215322-A2 Colored thermoplastic resin composition MILLIKEN RESEARCH CORPORATION (US) 1987-03-25 EP disclosed
US-4640690-A Colored thermoplastic resin composition containing a colorant having an alkylenoxy-substituted chromophore group MILLIKEN RESEARCH CORPORATION (US) 1987-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270651-A1 HAIR CARE COMPOSITION CONTAINING POLYMERIC COLORANT CUTA, MC1R, TYR ALDH1A1 897/4885HSD17B10 252/4885HIF1A 843/4885
US-12042556-B2 Oxidative hair cream composition containing polymeric colorant LPO, COX5A, GPX4 ALDH1A1 87/4885HSD17B10 123/4885HIF1A 893/4885
US-11684560-B2 Oxidative hair cream composition containing polymeric colorant LPO, COX5A, GPX4 ALDH1A1 87/4885HSD17B10 123/4885HIF1A 893/4885
US-20230270658-A1 OXIDATIVE HAIR CREAM COMPOSITION CONTAINING POLYMERIC COLORANT LPO, COX5A, GPX4 ALDH1A1 87/4885HSD17B10 123/4885HIF1A 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.