Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RHOC | P08134 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845735 | 0.91 | POLB (0.45) | POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL845049 | 0.75 | LMNA (0.48) | POLBKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL845422 | 0.70 | KMT2A (0.46) | POLBKMT2AMAPTALDH1A1RHOC | |
| SCHEMBL845592 | 0.70 | KMT2A (0.64) | POLBKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL845181 | 0.69 | MAPT (0.69) | POLBMAPTALDH1A1 | |
| SCHEMBL845598 | 0.69 | RAB9A (0.46) | POLBKMT2AMAPTALDH1A1RHOC | |
| SCHEMBL845338 | 0.68 | RHOC (0.48) | POLBKMT2AALDH1A1RHOCRHOA | |
| SCHEMBL873200 | 0.68 | RHOC (0.48) | KMT2AMAPTALDH1A1RHOCRHOA | |
| SCHEMBL845541 | 0.68 | RHOC (0.49) | POLBKMT2AMAPTALDH1A1RHOC | |
| SCHEMBL844934 | 0.68 | RHOC (0.51) | KMT2AMAPTALDH1A1RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |